New Data Suggest ExoFlo is Poised for a Quantum Leap in the Fight Against COVID-19
AUSTIN, Texas, Aug. 27, 2020 /PRNewswire/ -- Direct Biologics, LLC announces a rapid acceleration of the investigational use of ExoFlo™ for treatment of COVID-19 as new mechanisms of SARS-CoV-2 have been revealed. Published in Lung Cellular and Molecular Physiology in August, a recent research collaboration by bioinformatics experts in the United States and Poland suggests that the SARS-CoV-2 viral genome may be binding to specific human microRNA (miRNA) in the manner of an epigenetic "sponge"— essentially inhibiting normal downstream processes and facilitating viral hijacking and/or immune evasion. "These findings are highly interesting and pertinent to our research," states Dr. Vik Sengupta, Chief Medical Officer, "especially since the authors' exomic analysis reveals the depletion of multiple miRNA targets. These data complement our recent findings that ExoFlo contains multiple miRNA that may specifically inhibit the SARS-CoV-2 viral invasion and modulate the systemic hyperinflammatory response, known as Cytokine Storm." Dr. Sengupta further elaborates that ExoFlo may have other therapeutic mechanisms, stating that "In April 2020, we already treated 24 patients with COVID-19 associated Acute Respiratory Distress Syndrome (ARDS), reversing hypoxia in 17 out of the 24 patients, who were then discharged within 5-6 days. Our results suggest that ExoFlo may be fortifying host immunity by reconstituting T-cells
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